jerry-feng-2021.jpgAssistant Dean for Research and
Professor, Department of Biomedical Sciences
Member of the Texas A&M Graduate Faculty 

3302 Gaston Ave.
Dallas, Texas 75246
Phone: 214-370-7235
Fax: 214-874-4538

Google Scholar Profile

Education and Post-Graduate Training

  • Postdoctoral Fellowship, Medicine, University of Texas Health Science Center, San Antonio (1991-1995)
  • Postdoctoral Fellowship, Physiology, Medicine, University of Michigan, Ann Arbor, MI (1985-1987)
  • Ph.D., Physiology, University of Connecticut, Storrs, CT (1991)
  • M.S., Physiology, University of Qindao, Medical College, Qindao, China (1982)
  • B.S., Medicine, University of Qindao, Medical College, Qindao, China (1976)

Career History

  • Assistant Dean for Research, Texas A&M University College of Dentistry (2016-present)
  • Associate Director of Faculty Development, Texas A&M Health Science Center (2018-2019)
  • Associate Head of Department of Biomedical Sciences, Texas A&M University College of Dentistry (2013-present)
  • Professor with tenure,  Department of Biomedical Sciences, Texas A&M University College of Dentistry (2007-present)
  • Professor with tenure, Department of Oral Biology, University of Missouri-Kansas City (2006-2007)
  • Associate Professor with tenure, Department of Oral Biology, University of Missouri-Kansas City (1998-2006)
  • Research Assistant Professor, Department of Pediatric Dentistry, University of Texas Health Science Center, School of Dentistry, San Antonio (1996-1998)
  • Research Assistant Professor, Department of Medicine (Endocrinology), University of Texas Health Science Center, School of Dentistry, San Antonio (1997-1998)
  • Assistant Professor, Department of Pediatric Dentistry, University of Texas Health Science Center, School of Dentistry, San Antonio (1996-1997)

Honors and Awards

2019            Keynote Speaker, the IADR Asia Pacific Region, Brisbane, Australia

2019            Fellows, the American Society of Bone and Mineral Research

2018            Regents Professor, Texas A&M University Health Science Center

2018            Keynote Speaker, Australian & New Zealand Orthopaedic Research Society Conference at Perth, Australia

2017            TX A&M Presidential Impact Fellows

2013            Keynote Speaker at AAA regional meeting, Dallas TX

2011            Visiting Professor Lectureship, Institute of Health and Biomedical Innovation, Queensland University of                             Technology, Brisbane, Queensland, Australia

2011            Distinguished Scientist Award, International Association for Dental Research, San Diego, CA

2008            Raine Visiting Professor Lectureship, Raine Medical Research Foundation, University of Western Australia                        (Perth, Australia, March)

2006            Keynote Speaker at Annual Meeting of American Association for Dental Research, Orlando, FL

2005/2017  William Gies Award, International Association for Dental Research/ American Association for Dental                                     Research (two times)

Teaching Interests 

Teaching responsibilities include:

Physiology (Dental students) and Hard Tissue Physiology (Graduate)

Research Interests

My research interests are bone, cartilage, tendon, and teeth. The most unique feature of my research is thinking beyond box. Examples are:

  1. Demonstration of distinct regulation mechanisms used in tooth crown and tooth root, respectively (Zhang et al. JBMR, 2015);
  2. Demonstration of the direct transdifferentiation from a terminated chondrocyte into a mature bone cell, which count for >80% bone cells in the TMJ ramus (Jing et al. JDR, 2015);
  3. Demonstration of a new concept: the Chondrogenesis and osteogenesis are one continuous developmental and lineage defined biological process (Jing et al. Scientific Report 2017);
  4. Demonstration of the endocrine function of osteocyte: secretion of a phosphorus regulatory hormone named FGF23, leading to hypophosphatemia rickets when DMP1 is mutated in patients or Dmp1 is removed in mice (Feng et al. Nat. Genet. 2006); and
  5. Demonstrate that osteocytes, instead of being “retired bone builders” are the real driving forces, the "engines", in bone formation and bone remodeling a recent discoveries of cell transdifferentiation from tendon cells to bone cells or to chondrocytes in normal skeletal growth and remodeling.

Currently, the mainstream centers on manipulating cells from bone stem cell niches for bone regeneration. In contrast, we focus on tendon, as there is a striking difference between bones with and without tendon attachment and the whole skull (except for calvarial bone) is wrapped with rich tendons. Our pilot data revealed two key osteogenic features of tendon: directly forming a 3rd type of bone during skeletal growth, and cell plasticity robust capability to switch to bone cell upon trauma or inflammation (as an endogenous alternative cell source for bone regeneration).

Recent Grants

Ongoing Research Support

  1. R01 DE025659 Feng 12/2016-11/2021

Chondrocyte-derived bone cells define the TMJ pattern and remodeling

The goal of this project is to elucidate fundamental aspects of how the mandibular condylar cartilage grows and remodel compared to limbs.

Role: PI


  1. R01 DE0 DE028291 Feng 04/01/2021-03/31/2026


The tendon cell is a robust alternative lineage for bone repair upon trauma or inflammation.

The goal of this proposal is to investigate the mechanisms underlying the tendon cell’s capacity to switch to an osteogenic state for craniofacial bone formation during trauma and inflammation.

Role: PI


  1. R01 DE0 DE028291 Feng 02/2018-01/2023

NIDCR/NIH Regulating Niche of Periodontium Mesenchymal Stem Cells under the Physiological Condition

The major goal is to study the impact of different local environment factors on the mesenchymal stem cell niche.

Role: PI


  1. R21DE029860 Liu 7/1/2020 – 6/30/2022


Polarization of dental pulp stem cells

This grant is aimed at identifying the biophysical and biochemical factors that initiate and regulate the polarization of dental pulp stem cells.

Role: Co-PI


  1. R01 DE029808 Liu 04/01/2021-03/31/2026


MINE-MS for horizontal bone loss treatment

The goal of this proposal is to investigate how to repair bone loss using bioengineering approaches.

Role: Co-PI


  1. K08DE028593 Jing 12/7/2020 – 11/30/2025


To define the novel roles of endochondrogenesis in mandible formation and trauma repair

This grant is aimed at training Yan Jing (DDS/PhD) as an independent clinician scientist.

Role: PI Mentor


Completed Research Support (Past three years)

  1. R01 DE025014 Feng 07/01/15 – 06/30/2020

Biphasic Roles of OSX-WNT-B-Catenin Signaling Pathway in Tooth Root Formation

The goal is to define the mechanisms by which postnatal root formation via the Osx-Wnt-b-catenin signaling.

Role: PI

  1. R01 DK101730-01A1 Aline Martin 07/01/15 – 06/30/2020

Regulation of FGF23 by DMP1 in Health and Chronic Kidney Disease

This is a subcontract for analyzing the bone specimens using SEM and FITC labeling techniques.

Role: Co-PI

  1. R01 DE024797-01A1 Stephen E Harris 07/01/15 – 06/30/2020

Bmp2 and Sost Genes and Their Interactions in Stem Cells of the Periodontium

This is a subcontract for analyzing the jawbone specimens using SEM and FITC labeling techniques.

Role: Co-PI

Selected Publications

Recent 10 year publications

  1. X Xie, C Xu, H Zhao, J Wang, JQ Feng A biphasic feature of Gli1+-mesenchymal progenitors during cementogenesis that is positively controlled by Wnt/β-catenin signaling J Dent Res. accepted
  2. Chi Ma, Yan Jing, Hui Li, Ke Wang, Zheng Wang, Chunmei Xu, Xiaolin Sun, Deepak Kaji, Xianglong Han, Alice Huang, Jian Q Feng Scx Lin cells directly form a subset of chondrocytes in temporomandibular joint that are sharply increased in Dmp1-null mice 2021 Jan;142:115687. doi: 10.1016/j.bone.2020.115687. Epub 2020 Oct 12.
  3. Jing, Y., Simmer, P., Feng, JQ. Cell Lineage Tracing: Colocalization of Cell Lineage Markers with a Fluorescent Reporter Methods Mol Biol 2021;2230:325-335. doi: 10.1007/978-1-0716-1028-2_18.
  4. D Jing, C Li, K Yao, X Xie, P Wang, H Zhao, JQ Feng, Z Zhao, Y Wu, J Wang The vital role of Gli1+ mesenchymal stem cells in tissue development and homeostasis J Cel. Physiol First published: 02 February 2021
  5. Yi Men, Yuhong Wang, Yating Yi, Dian Jing, Wenjing Luo, Bo Shen, William Stenberg, Yang Chai, Woo-Ping Ge, Jian Q Feng, Hu Zhao Gli1+ periodontium stem cells are regulated by osteocytes and occlusal force Dev Cell 2020 Sep 14;54(5):639-654.e6. doi: 10.1016/j.devcel.2020.06.006.
  6. Lin Shuxian, Methani Mohammad Mujtaba and Feng Jian Q. (2020) Transition of Osteoblasts to Osteocytes. In: Zaidi, M (ed.) Encyclopedia of Bone Biology. vol. 1, pp. 491-498. Oxford: Academic Press
  7. Li H, Jing Y, Zhang R, Zhang Q, Wang J, Martin A, Feng JQ. Hypophosphatemic rickets accelerate chondrogenesis and cell trans-differentiation from TMJ chondrocytes into bone cells via a sharp increase in β-catenin. Bone. 2020 Feb;131:115151
  8. J Wang, Y Jiang, X Xie, S Zhang, C Xu, Y Zhou, JQ Feng The identification of critical time windows of postnatal root elongation in response to Wnt/β‐catenin signaling Oral Dis. 2020 Dec 12. doi: 10.1111/odi.13753.
  9. J Wang, X Xie, NA Muench, D Massoudi, C Xu, DS Greenspan, JQ Feng Proteinase bone morphogenetic protein 1, but not tolloid‐like 1, plays a dominant role in maintaining periodontal homeostasis J Periodontol. 2020 Nov 9. doi: 10.1002/JPER.20-0354. Online ahead of print.
  10. Yan Jing, Zheng Wang, Hui Li, Chi Ma, Jian Feng Chondrogenesis Defines Future Skeletal Patterns Via Cell Transdifferentiation from Chondrocytes to Bone Cells Curr Osteoporos Rep. 2020 Jun;18(3):199-209. doi: 10.1007/s11914-020-00586-3
  11. Y Xie, N Su, J Yang, Q Tan, S Huang, M Jin, Z Ni, B Zhang, D Zhang, F Luo, H Chen, X Sun, JQ Feng, H Qi, L Chen FGF/FGFR signaling in health and disease Signal Transduct Target Ther. 2020 Sep 2;5(1):181. doi: 10.1038/s***************-7.
  12. VLP MOLLI, J Anubhav, FU Jiangnan, WU Yingjie, JQ Feng, Q. Wang Osteons and osteocyte lacunae in belanger’s treeshrews (Tupaia belangeri chinensis)-A qualitative image comparative study Acta Anthropologica Sinica 2020 39 (04), 564
  13. H Cao, Q Yan, D Wang, Y Lai, B Zhou, Q Zhang, W Jin, S Lin, Y Lei, L Ma, Y Guo, Y Wang, Y Wang, X Bai, C Liu, JQ Feng, C Wu, D Chen, X Cao, G Xiao Focal adhesion protein Kindlin-2 regulates bone homeostasis in mice Bone Res. 2020 Jan 2;8:2. doi: 10.1038/s41413-019-0073-8. eCollection 2020
  14. Tingjun Liu, Jun Wang, Xudong Xie, Ke Wang, Tingting Sui, Di Liu, Liangxue Lai, Hu Zhao, Zhanjun Li, Jian Q. Feng DMP1 Ablation in The Rabbit Results in Mineralization Defects and Abnormalities in Harversian Canal/Osteon Microarchitectures J Bone Miner Res 2019Jun;34(6):1115-1128
  15. Jing Y, Li C, Feng JQ. Application of Cell Lineage Tracing Combined with Immunofluorescence in the Study of Dentinogenesis. Methods Mol Biol. 2019;1922:39-48.
  16. Gao J, Qin A, Liu D, Ruan R, Wang Q, Yuan J, Cheng TS, Filipovska A, Papadimitriou JM, Dai K, Jiang Q, Gao X, Feng JQ, Takayanagi H, Zhang C, Zheng MH Endoplasmic reticulum mediates mitochondrial transfer within the osteocyte dendritic network Sci Adv. 2019 Nov 20;5(11):eaaw7215. doi: 10.1126/sciadv.aaw7215.
  17. Chen H, Zhang J, Wang Y, Cheuk KY, Hung ALH, Lam TP, Qiu Y, Feng JQ, Lee WYW, Cheng JCY Abnormal lacuno-canalicular network and negative correlation between serum osteocalcin and Cobb angle indicate abnormal osteocyte function in adolescent idiopathic scoliosis. FASEB J. 2019 Dec 1;33(12):13882-13892
  18. Wang Y, Yan Q, Zhao Y, Liu X, Lin S, Zhang P, Ma L, Lai Y, Bai X, Liu C, Wu C, Feng JQ, Chen D, Cao H, Xiao G Focal adhesion proteins Pinch1 and Pinch2 regulate bone homeostasis in mice. JCI Insight. 2019 Nov 14;4(22).
  19. Wang FM, Hu Z, Liu X, Feng JQ, Augsburger RA, Gutmann JL, Glickman GN Resveratrol represses tumor necrosis factor α/c-Jun N-terminal kinase signaling via autophagy in human dental pulp stem cells. Arch Oral Biol. 2019 Jan;97:116-121
  20. Wu J, Feng JQ, Wang X In Situ Hybridization on Mouse Paraffin Sections Using DIG-Labeled RNA Probes. Methods Mol Biol. 2019;1922:163-171.
  21. X Xie, J Wang, K Wang, C Li, S Zhang, D Jing, C Xu, X Wang, H Zhao, J Q Feng Axin2(+)-Mesenchymal PDL Cells, Instead of K14(+) Epithelial Cells, Play a Key Role in Rapid Cementum Growth J Dent Res. 2019 Oct;98(11):1262-1270. doi: 10.1177/0022034519871021.
  22. Yi Y, Men Y, Jing D, Luo W, Zhang S, Feng JQ, Liu J, Ge WP, Wang J, Zhao H.3-dimensional visualization of implant-tissue interface with the polyethylene glycol associated solvent system tissue clearing method. Cell Prolif. 2019 May;52(3):e12578.
  23. Zhao W, Li X, Peng Y, Qin Y, Pan J, Li J, Xu A, Ominsky MS, Cardozo C, Feng JQ, Ke HZ, Bauman WA, Qin W Sclerostin Antibody Reverses the Severe Sublesional Bone Loss in Rats After Chronic Spinal Cord Injury. Calcif Tissue Int. 2018 Jun 21. doi: 10.1007/s00223-018-0439-8.
  24. Jing D, Zhang S, Luo W, Gao X, Men Y, Ma C, Liu X, Yi Y, Bugde A, Zhou BO, Zhao Z, Yuan Q, Feng JQ, Gao L, Ge WP, Zhao H. Tissue clearing of both hard and soft tissue organs with the PEGASOS method. Cell Res. 2018 28(8):803-818
  25. Wang L, Fang B, Fujiwara T, Krager K, Gorantla A, Li C, Feng JQ, Jennings ML, Zhou J, Aykin-Burns N, Zhao H. Deletion of ferroportin in murine myeloid cells increases iron accumulation and stimulates osteoclastogenesis in vitroand in vivo. J Biol Chem. 2018 Jun 15;293(24):9248-9264
  26. Hominick D, Silva A, Khurana N, Liu Y, Dechow PC, Feng JQ, Pytowski B, Rutkowski JM, Alitalo K, Dellinger MT.VEGF-C promotes the development of lymphatics in bone and bone loss. Elife. 2018 Apr 5;7. pii: e34323. doi: 10.7554/eLife.34323.
  27. Liu M, Kurimoto P, Zhang J, Niu QT, Stolina M, Dechow PC, Feng JQ, Hesterman J, Silva MD, Ominsky MS, Richards WG, Ke H, Kostenuik PJ Sclerostin and DKK1 Inhibition Preserves and Augments Alveolar Bone Volume and Architecture in Rats with Alveolar Bone Loss.J Dent Res. 2018 Aug;97(9):1031-1038
  28. Zheng J, Chen S, Albiero ML, Vieira GHA, Wang J, Feng JQ, Graves DT Diabetes Activates Periodontal Ligament Fibroblasts via NF-κB In Vivo.J Dent Res. 2018 May;97(5):580-588.
  29. Yan WJ, Ma P, Tian Y, Wang JY, Qin CL, Feng JQ, Wang XF. The importance of a potential phosphorylation site in enamelin on enamel formation. Int J Oral Sci. 2017 Nov 29;9(11):e4. doi: 10.1038/ijos.
  30. Chaoyuan Li, Yan Jing, Ke Wang, Yinshi Ren, Xiaohua Liu, Xiaofang Wang, Zuolin Wang, Hu Zhao, and Jian Q. Feng Int J Biol Sci 2018; 14(7):693-704. doi:10.7150/ijbs.25712
  31. Jing Yan, Jing JJ, Ke Wang, Kevin Chan, Harris SE, Hinton RJ, Feng JQ Vital roles of -catenin in trans-differentiation of chondrocytes to bone cells Int J Biol Sci 2018; 14(1):1-9. doi:10.7150/ijbs.23165
  32. Ma C, Qu T, Chang B, Jing Y, Feng JQ, Liu X 3D Maskless Micropatterning for Regeneration of Highly Organized Tubular Tissues Adv Healthc Mater 2018 Feb;7(3). doi: 10.1002/adhm.201700738.
  33. Jing Yan, Jing JJ, Ye L, Liu X, Harris SE, Hinton RJ, Feng JQ Chondrogenesis and osteogenesis are one continuous developmental and lineage defined biological process Scientific Report 7: 10020 | DOI:10.1038/s41598-017-10048-z
  34. Wang J, Massoudi D, Ren Y, Muir AM, Harris SE, Greenspan DS, Feng JQ. BMP1 and TLL1 are required for maintaining periodontal homeostasis J Dent Res 96: 5, page(s): 578-585 2017
  35. Wang J, Muir AM, Ren Y, Massoudi D, Greenspan DS, Feng JQ. Essential roles of bone morphogenetic protein-1 and mammalian tolloid-like 1 in postnatal root dentin formation. J Endod. 2017 Jan;43(1):109-115.
  36. Hinton RJ, Jing Y, Jing J, Feng JQ Roles of Chondrocytes in Endochondral Bone Formation and Fracture Repair J Dent Res Jan;96(1):23-30. 2017
  37. Wang J, Feng JQ. Signaling Pathways Critical for Tooth Root Formation. J Dent Res. 2017 Oct;96(11):1221-1228. doi: 10.1177/0022034517717478. Epub 2017 Jun 30.
  38. Xu H, He Y, Feng JQ, Shu R, Liu Z, Li J, Wang Y, Xu Y, Zeng H, Xu X, Xiang Z, Xue C, Bai D, Han X. Wnt3α and transforming growth factor-β induce myofibroblast differentiation from periodontal ligament cells via different pathways. Exp Cell Res. 2017 Apr 15;353(2):55-62. PMID: 28223136
  39. Owen, K. M., Campbell, P. M., Feng, JQ., Dechow, P. C., & Buschang, P. H. Elevation of a full-thickness mucoperiosteal flap alone accelerates orthodontic tooth movement. Am J Orthod Dentofacial Orthop, 152(1), 49-57. doi:10.1016/j.ajodo.2016.11.026, 2017.
  40. Moon J, Zhou H, Zhang LS, Tan W, Liu Y, Zhang S, Morlock LK, Bao X, Palecek SP, Feng JQ, Williams NS, Amatruda JF, Olson EN, Bassel-Duby R, Lum L Blockade to pathological remodeling of infarcted heart tissue using a porcupine antagonist. Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1649-1654. PMID: 28143939
  41. Kamiya N, Yamaguchi R, Aruwajoye O, Kim AJ, Kuroyanagi G, Phipps M, Adapala NS, Feng JQ, Kim HK. 2017. Targeted disruption of nf1 in osteocytes increases fgf23 and osteoid with osteomalacia-like bone phenotype. J Bone Miner Res. 32(8):1716-1726.
  42. Yan Jing, Robert J. Hinton, Kevin S. Chan, Jian Q. Feng Co-localization of Cell Lineage Markers and the Tomato Signal. JOV J Vis Exp. 2016 Dec 28;(118). doi: 10.3791/54982.
  43. Kamiya N, Shuxian L, Yamaguchi R, Phipps M, Aruwajoye O, Adapala NS, Yuan H, Kim HK, Feng JQ. 2016. Targeted disruption of bmp signaling through type ia receptor (bmpr1a) in osteocyte suppresses sost and rankl, leading to dramatic increase in bone mass, bone mineral density and mechanical strength. Bone. 91:53-63.
  44. Zhang Y,Xu JRuan YCYu MKO'Laughlin MWise HChen DTian LShi DWang JChen SFeng JQChow DHXie XZheng LHuang LHuang SLeung KLu NZhao LLi HZhao DGuo XChan KWitte FChan HCZheng YQin L Implant-derived magnesium induces local neuronal production of CGRP to improve bone-fracture healing in rats. Nat Med. Oct;22(10):1160-1169, 2016
  45. Hui Y, Li Y, Jing Y, Feng JQ, Ding Y miRNA-101 acts as a tumor suppressor in oral squamous cell carcinoma by targeting CX chemokine receptor 7. Am J Transl Res. 2016 Nov 15;8(11):4902-4911. eCollection 2016.
  46. Shuxian Lin, Kathy K H Svoboda, Jian Q Feng & Xinquan Jiang The biological function of type I receptors of bone morphogenetic protein in bone. Bone Research 4, Article number: 16005 2016
  47. Qi Zhang, Shuxian Lin, Ying Liu, Kevin Yan, Baozhi Yuan, and J.Q. Feng Dmp1 Null Mice Develop a Unique Osteoarthritis-like Phenotype Int J Biol Sci. 2016 Sep 15;12(10):1203-1212 PMID: 27766035 PMCID: PMC5069442
  48. Ren, Y., Han, X., Jing, Y., Yuan, B., Ke, H., Liu, M., and Feng, J.Q Sclerostin antibody (Scl-Ab) improves osteomalacia phenotype in dentin matrix protein 1(Dmp1) knockout mice with little impact on serum levels of phosphorus and FGF23. Matrix Biol. May-Jul;52-54:151-61, 2016; PMID: 26721590 PMCID: PMC4875883
  49. Bruno Ruest, Hamid Ranjbaran, Eric J. Tong, Kathy K.H. Svoboda and Jian Q. Feng Activation of RANKL and MMP production in periodontal fibroblasts by endothelin signaling. Periodontology, 17:1-16 2015
  50. Hinton RJ, Jing J, Feng JQ. Genetic Influences on Temporomandibular Joint Development and Growth. Curr Top Dev Biol. 2015;115:85-109. doi: 10.1016/bs.ctdb.2015.07.008. Epub 2015 Oct 1
  51. Ling Qin, Dong Yao, Lizhen Zheng, Wai-Ching Liu, Zhong Liu, Ming Lei, Le Huang, Xinhui Xie, Xinluan Wang, Yang Chen, Xinsheng Yao, Jiang Peng, He Gong, James F Griffith, Yanping Huang, Yongping Zheng, Jian Q Feng, Ying Liu, Shihui Chen, Deming Xiao, Daping Wang, Jiangyi Xiong, Duanqing Pei, Peng Zhang, Xiaohua Pan, Xiaohong Wang, Kwong-Man Lee, Chun-Yiu Cheng Phytomolecule icaritin incorporated PLGA/TCP scaffold for steroid-associated osteonecrosis: Proof-of-concept for prevention of hip joint collapse in bipedal emus and mechanistic study in quadrupedal rabbits Biomaterials 59:125-143, 2015
  52. Alvares K, Ren Y, Feng JQ, Veis A Expression of the invertebrate sea urchin P16 protein into mammalian MC3T3 osteoblasts transforms and reprograms them into "osteocyte-like" cells. J Exp Zool B Mol Dev Evol. 2015 Nov 19. doi: 10.1002/jez.b.22663.
  53. Rangiani A, Jing Y, Ren Y, Yadav S, Taylor R, Feng JQ. Critical roles of periostin in the process of orthodontic tooth movement. Eur J Orthod. 2015 Oct 7. pii: cjv071.
  54. Maginot M, Lin S, Liu Y, Yuan B, Feng JQ, Aswath PB. The in vivo role of DMP-1 and serum phosphate on bone mineral composition. Bone. 2015 Dec;81:602-13
  55. Jing J, Hinton RJ, Feng JQ. Bmpr1a Signaling in Cartilage Development and Endochondral Bone Formation. Vitam Horm 99:***********.
  56. Ren Y, Han X, Ho SP, Harris SE, Cao Z, Economides AN, Qin C, Ke H, Liu, M, Feng JQ.  Removal of SOST or blocking its product sclerostin rescues defects in the periodontitis mouse model, FESAB J 2015 Jul;29(7):2702-11
  57. Yan Jing, Xin Zhou, Xianglong Han, Junjun Jing, Klaus von der Mark, Jingya Wang, Benoit de Crombrugghe, Robert J Hinton, Jian Q. Feng Chondrocytes Directly Transform into Bone Cells in Mandible Condyle Growth Dent. Res 94(12):1668-75 2015
  58. Feng, JQ, H Zhang and C Qin Letter to the Editor, “Osterix Regulates Tooth Root Formation in a Site-specific Manner” J Dent Res. 94(9): 1326 2015
  59. Qin W, Li X, Peng Y, Harlow LM, Ren Y, Wu Y, Li J, Qin Y, Sun J, Zheng S, Brown T, Feng JQ, Ke HZ, Bauman WA, Cardozo CC Sclerostin antibody preserves the morphology and structure of osteocytes and blocks the severe skeletal deterioration after motor-complete spinal cord injury in rats J Bone Miner Res. 2015 May 12. doi: 10.1002/jbmr.2549. [Epub ahead of print]
  60. Qu T, Jing J, Ren Y, Ma C, Feng JQ, Yu Q, Liu X. Complete pulpodentin complex regeneration by modulating the stiffness of biomimetic matrix. Acta Biomater. Apr;16:60-70. doi: 10.1016/ j.actbio.2015
  61. Velten M,Lin SLiu YYuan BFeng JQAswath PB The in vivo role of DMP-1 and serum phosphate on bone mineral composition, Bone 81 602–613 2015
  62. Hui X, Ding B, Ruest LB, Feng JQ, Guo Y, Tian Y, Jing Y, He Y and Xiang-Long Han. Expression analysis of α-SMA and tenascin-C in the periodontal ligament under orthodontic loading or in vitro culture. International Journal of Oral Science 7, 232–241 2015
  63. Chen S, Feng J, Bao Q, Li A, Zhang B, Shen Y, Zhao Y, Guo Q, Jing J, Lin S, Zong Z. Adverse effects of osteocytic constitutive activation of ß-catenin on bone strength and bone growth J Bone Miner Res. 2015 Jul;30(7):1184-94. doi: 10.1002/jbmr.2453
  64. Cao Z, Liu R, Zhang H, Liao H, Zhang Y, Hinton RJ, and Feng JQ. Osterix controls cementoblast differentiation through downregulation of Wnt-signaling via enhancing DKK1 expression, Int J Biol Sci. 2015 Feb 5;11(3):335-44. doi: 10.7150/ijbs.10874. eCollection 2015
  65. Wang X, Wang J, Liu Y, Yuan B, Ruest LB, Feng JQ, and Qin C. The specific role of FAM20C in dentinogenesis J Dent Res 2015 Feb;94(2):330-6. doi: 10.1177/0022034514563334.
  66. Zhang H, Jiang Y, Qin C, Liu Y, Ho SP and Feng JQ. Essential role of Osterix for tooth root but not crown dentin formation J Bone Miner Res  2015 Apr;30(4):742-6. doi: 10.1002/jbmr.2391. PMID: 25349111
  67. Ren Y, Lin S, Jing Y, Dechow PC and Feng JQ. A novel way to statistically analyze morphologic changes in osteocytes in Dmp1 null mice, See comment in PubMed Commons below Connect Tissue Res. 2014 Aug;55 Suppl 1:129-33. doi: 10.3109/03008207. “Nice method that can be used on a variety of mouse models to better understand osteocyte biology” (a comment from one of reviewers).
  68. Huang Y, Meng T, Wang S, Zhang H, Mues G, Qin C, Feng JQ, D'Souza RN, Lu Y. Twist1-and Twist2-haploinsufficiency results in reduced bone formation PLoS One. 2014 Jun 27;9(6):e99331. doi: 10.1371
  69. Jing J, Hinton RJ, Jing Y, Liu Y, Zhou X and Feng JQ Osterix couples chondrogenesis and osteogenesis in post-natal condylar growth, Journal of Dental Research 2014 Oct;93(10):1014-21. doi: 10.1177 October Issue 2014 cover page
  70. Lin S, Zhang Q, Zhang H, Yan K, Ying L, Lu Y and Feng Nucleus-targeted Dmp1 transgene fails to rescue dental defects in Dmp1 null Mice Int J Oral Sci 2014 Sep;6(3):133-41 doi: 10.1038/ijos.2014.44.
  71. Movérare-Skrtic S, Henning P, Liu X, Nagano K, Saito H, Börjesson AE, Sjögren K, Windahl SH, Farman H, Kindlund B, Engdahl C, Koskela A, Zhang FP, Eriksson EE, Zaman F, Hammarstedt A, Isaksson H, Bally M, Kassem A, Lindholm C, Sandberg O, Aspenberg P, Lars Sävendahl L, Feng JQ, Tuckermann J, Tuukkane J, Poutanen M, Baron R, Lerner UH, Gori F, and Ohlsson. C1 Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility fractures Nature Medicine, 20, 1279–1288 (2014) doi:10.1038/nm.3654
  72. Lin S, Zhang Q, Cao Z, Lu Y, Zhang H, Yan K, Liu Y, McKee MD, Qin C, Zhi Chen, Z and Feng JQ. Constitutive nuclear expression of dentin matrix protein 1 fails to rescue the Dmp1-null phenotype J Biol Chem 2014 Aug 1;289(31):21533-43. doi: 10.1074/jbc.M113.543330. Epub 2014 Jun 10.
  73. Muir AM, RenY, Hopkins Butz D, Davis NA, Blank RD,. Birk DE, Lee SJ, Rowe D, Feng JQ and Daniel S. Greenspan DS. Induced ablation of Bmp1 and Tll1 produces osteogenesis imperfecta in mice. 2014 Human Molecular Genetics, 15;23(12):3085-101. doi: 10.1093/hmg/ddu013
  74. Zhibin D, Ivanovski S, Hamlet SM, Feng JQ, Xiao Y. The ultrastructuralr relationship between osteocytes and dental implants following osseointegration Clin Implant Dent Relat Res. 2014 Jul 10. doi: 10.1111/cid.12257
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  76. Q Tu, Jing J, Jiang Y, Taylor RJ, Feng JQ, Geiger B, Liu X. Magnesium-containing nano-structured hybrid scaffolds for enhanced dentin regeneration Tissue Engineering Part A, 2014, Mar 4. [Epub ahead of print], PMID: 24593189
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