Texas A&M University College of Dentistry

Xiaofang Wang, PhD, MDS

Professor Department of Biomedical Sciences | College of Dentistry
Contact
  • 214-370-7229
  • 3302 Gaston Ave
    Dallas, TX 75246
  • Fax: 214-874-4538
Groups and Affiliations

Biography

Career History

  • Professor, with tenure, Texas A&M College of Dentistry (2026 - Present)
  • Associate Professor, with tenure, Texas A&M College of Dentistry (2019 - 2026) 
  • Assistant Professor, Texas A&M College of Dentistry (2017 - 2019)
  • Research Assistant Professor, Baylor College of Dentistry/Texas A&M College of Dentistry (2012 - 2017)
  • Postdoctoral Associate, Department of Biomedical Sciences, Texas A&M University Baylor College of Dentistry (2008 -2012)
  • Postdoctoral Associate, Department of Oral Biology, Ohio State University, College of Dentistry (2006- 2008) 

Education

  • Ph.D. Fourth Military Medical University, 2003
  • Exchange Student Shanghai Institutes for Biological Sciences, Chinese Academy of Science 2001-2003
  • M.D.S. Fourth Military Medical University College of Dentistry, Xi'an, China, 2000
  • D.D.S. Fourth Military Medical University College of Dentistry, Xi'an, China, 1995

Awards & Honors

  • Ad Hoc Reviewer of NIDCR CSR Study Section 2026
  • Editor of Distinction Award (Springer Nature) 2025, 2026
  • President, IADR Craniofacial Biology Group 2026
  • President-elect, IADR Craniofacial Biology Group 2025
  • Vice President, IADR Craniofacial Biology Group 2024
  • Tenure & Promotion Committee, Texas A&M University (2024-2026)
  • Standing Member, NIDCR DSR Study Section 2021-2027
  • Ad Hoc Reviewer of NIDCR ZDE1 Study Section 2020
  • Secretary/Treasurer of IADR Craniofacial Biology Group 2020-2023
  • Ad Hoc Reviewer of NIDCR SBDD Study Section 2020
  • Basic Research Award Texas A&M University College of Dentistry, 2019
  • Featured Symposium for Press Release (Organizer & Chair, 2018 AADR)
  • Associate Editor, Frontiers in Endocrinology Since 2022
  • Editorial Board of Scientific Reports Since 2018
  • Editorial Board of PLoS One Since 2018
  • Editorial Board of Oral Diseases Since 2018
  • Abstract Reviewer of ASBMR Annual Meeting Since 2018
  • Abstract Reviewer of AADR/IADR Annual Meeting Since 2017
  • Ad Hoc Reviewer of NIDCR DSR Study Section Since 2016
  • Harold M. Frost Young Investigator Award (2013 ASBMR)
  • Scientific Advisory Board of Journal of Endodontics Since 2013
  • Ad Hoc Reviewer of 13 Scientific Journals Since 2012
  • 1st place of Bernard G. Sarnat Award (Sanjaya Thapa, 2025 IADR)
  • Finalist of Hatton Competition (Sanjaya Thapa, 2024 AADOCR)
  • Bloc Travel Grant Award (Veronica Camacho, 2022 AADOCR Annual Meeting)
  • Young Investigator Award (Changchun Dong, 2021 ASBMR Annual Meeting)
  • Young Investigator Travel Grant Award (Bikash Lamichanne, 2021 ASBMR Annual Meeting)
  • Young Investigator Award (Bikash Lamichanne, 2021 IADR, Mineralized Tissue Group)
  • ASBMR Young Investigator Award (Dong Yang, 2019 ASBMR Annual Meeting)
  • Invited Oral Presentation (Jingyi Wu, 2018 Bones & Teeth Gordon Conference)
  • Finalist of Hatton Competition (Tianyu Sun, 2018 AADR)
  • 1st place of Bernard Sarnat Awards (Ye Tian, 2016 IADR)
  • 1st place of Dental Student Oral Presentation (Derrick M. Crawford, 2016 AADR)

Teaching Interests

  • DDDS601 General Histology (Instructor)
  • OBIO 641 Technique in Cell & Molecular Biology (Course Director)
  • OBIO 642 Cell and Molecular Biology II (Course Director)
  • OBIO 610 Responsible Conduct in Biomedical Research (Instructor)
  • OBIO 630 Craniofacial Growth Track Mechanisms of Development (Instructor)
  • OBIO 631 Advanced Craniofacial Development & Anomalies (Instructor)
  • DDHS 3250 Biomedical Sciences I (Instructor)

Recent Grants

  • A Novel GTPase Regulator Governing the Regenerative Capacity of Murine Teeth. NIH/NIDCR, R01DE033676 (PI), $1,748,926, 09/12/2024-08/31/2029
  • The Role of a Rho GTPase Regulator, Known as “Din”, in Tooth Development. Texas A&M Health Science Center, SB-30 Mission-Specific Funding (PI), $99,990, 04/01/2024-08/31/2025
  • The Central Role of a Novel GTPase Regulator, Din, in the Homeostasis of Mesenchymal Stem Cells (MSCs) in Bones and Teeth. Texas A&M Health Science Center, Seedling Grant (PI), $60,000, 06/01/2024-08/31/2025
  • The Role of FAM20B-Catalyzed Proteoglycans in Tooth Development. NIH/NIDCR, K02DE028345 (PI), $746,230, 09/18/2018-08/31/2023
  • The Role of FAM20B-Catalyzed Proteoglycans in Tooth Development. NIH/NIDCR, R01DE026461 (PI), $1,763,440, 04/01/2017-03/31/2022
  • The Critical Role of a Novel Nuclear Protein in the Stem Cell Homeostasis of Mouse Incisors. Texas A&M University, TAMU Interdisciplinary Faculty T3 Award (PI), $30,000, 04/01/2021-03/31/2023
  • The Role of a Novel Nuclear Protein in Bone and Tooth Development. College of Dentistry, Texas A&M University, Seedling Grant (PI), $10,000, 09/01/2019-08/31/2020
  • EZH2 and Endometrial Cancer. Texas A&M University, TAMU Interdisciplinary Faculty T3 Award (Co-I), $30,000, 04/01/2018-03/31/2020
  • The Role of FAM20C in the Phosphorylation of SIBLING Proteins. NIH/NIDCR, R03DE023873 (PI), $218,250, 04/01/2014 - 03/31/2016

Websites

Publications

2022 The phosphorylation of serine55 in enamelin is essential for murine amelogenesis
Dong C, Lamichhane B, Yamazaki H, Vasquez B, Wang J, Zhang Y, Feng JQ, Margolis HC, Beniash E, Wang X. (2022) The phosphorylation of serine55 in enamelin is essential for murine amelogenesis. Matrix Biol. S0945-053X(22)00090-7. DOI: 10.1016/j.matbio.2022.07.001.
2020 FAM20B-catalyzed glycosaminoglycans control murine tooth number by restricting FGFR2b signaling
Wu J, Tian Y, Han L, Liu C, Sun T, Li L, Yu Y, Lamichhane B, D’Souza RN, Millar SE, Krumlauf R, Ornitz DM, Feng JQ, Klein O, Zhao H, Zhang F, Linhardt RJ, Wang X. (2020) FAM20B-catalyzed glycosaminoglycans control murine tooth number by restricting FGFR2b signaling. BMC Biol. 18:87. https://doi.org/10.1186/s12915-020-00813-4.
2017 The importance of a potential phosphorylation site in enamelin on enamel formation
Yan W, Ma P, Tian Y, Wang J, Qin C, Feng JQ, Wang X. (2017) The importance of a potential phosphorylation site in enamelin on enamel formation. Int J Oral Sci. 9(11):e4. DOI: 10.1038/ijos.2017.41.
2016 The importance of serine phosphorylation of ameloblastin on enamel formation
Ma P, Yan W, Tian Y, He J, Brookes SJ, Wang X. (2016) The importance of serine phosphorylation of ameloblastin on enamel formation. J Dent Res. 95(12):1408-1414. DOI: 10.1177/0022034516661513.
2016 Inactivation of Fam20B in joint cartilage leads to chondrosarcoma and postnatal ossification defects
Ma P, Yan W, Tian Y, Wang J, Feng JQ, Qin C, Cheng YS, Wang X. (2016) Inactivation of Fam20B in joint cartilage leads to chondrosarcoma and postnatal ossification defects. Sci Rep. 6:39814. DOI: 10.1038/srep29814.
2016 FAM20C is the primary but not the only kinase for the SIBLINGs in bone
Yang X, Yan W, Tian Y, Ma P, Opperman LA, Wang X. (2016) FAM20C is the primary but not the only kinase for the SIBLINGs in bone. FASEB J. 30(1):121-8. DOI: 10.1096/fj.15-273607.
2015 Inactivation of Fam20B in the Dental Epithelium of Mice Leads to Supernumerary Incisors
Tian Y, Ma P, Liu C, Yang X, Crawford D, Yan W, Bai D, Qin C, Wang X. (2015) Inactivation of Fam20B in the Dental Epithelium of Mice Leads to Supernumerary Incisors. Eur J Oral Sci. 123(6):396-402.
2015 The Specific Role of FAM20C in Dentinogenesis
Wang X, Wang J, Liu Y, Yuan B, Ruest LB, Feng JQ, Qin C. (2015) The Specific Role of FAM20C in Dentinogenesis. J Dent Res. 94(2):330-336. DOI: 10.1177/0022034514563334.
2014 Overexpression of Dmp1 fails to rescue the bone and dentin defects in Fam20C knockout mice
Wang X, Wang J, Yuan B, Lu Y, Feng JQ, Qin C. (2014). Overexpression of Dmp1 fails to rescue the bone and dentin defects in Fam20C knockout mice. Connect Tissue Res. 55(4):299-303.
2013 The specific role of FAM20C in amelogenesis
Wang X, Jung J, Liu Y, Yuan B, Lu Y, Feng JQ, Qin C. (2013) The specific role of FAM20C in amelogenesis. J Dent Res 92(11):995-999. DOI: 10.1177/0022034513504588.
2012 FAM20C plays an essential role in the formation of murine teeth
Wang X, Wang S, Lu Y, Gibson MP, Liu Y, Yuan B, Feng JQ, Qin C. (2012) FAM20C plays an essential role in the formation of murine teeth. J Biol Chem 287(43):35934-35942. DOI: 10.1074/jbc.M112.386862.
2012 Inactivation of a novel FGF23 regulator, FAM20C, leads to hypophosphatemic rickets in mice
Wang X, Wang S, Li C, Gao T, Liu Y, Rangiani A, Sun Y, Hao J, George A, Lu Y, Groppe J, Yuan B, Feng J, Qin C. (2012) Inactivation of a novel FGF23 regulator, FAM20C, leads to hypophosphatemic rickets in mice. PLoS Genetics 8(5): e1002708. (Cover story of May issue) DOI: 10.1371/journal.pgen.1002708.
2010 Expression of FAM20C in the Osteogenesis and Odontogenesis of Mouse
Wang X, Hao J, Xie Y, Sun Y, Hernanderz B, Yamoah A, Prasad M, Zhu Q, Feng JQ, Qin C. (2010) Expression of FAM20C in the Osteogenesis and Odontogenesis of Mouse. J Histochem Cytochem 58(11):957-967. DOI: 10.1369/jhc.2010.956565.