Xiaohua Liu, PhD

Adjunct Professor Department of Biomedical Sciences | College of Dentistry
Contact
  • 214-370-7007
  • 3302 Gaston Avenue
    Dallas, TX 75246
  • Fax: 214-874-4538
Groups and Affiliations

Biography

Career History

  • Adjunct Professor, Texas A&M College of Dentistry (2021-present)
  • Associate Professor, Texas A&M College of Dentistry (2016 - 2021)
  • Assistant Professor,  Baylor College of Dentistry/Texas A&M College of Dentistry (2010 - 2016)

Education

  • Postdoctoral Fellowship University of Michigan, Ann Arbor, MI, 2010
  • Ph.D. Tsinghua University, Beijing, China, 2002
  • B.E. Tsinghua University, Beijing, China, 1997

Awards & Honors

  • Standing member of NIH ODCS study section (2021-2025)
  • Program chair of Society for Biomaterials Dental/Craniofacial Special Interest Group (2015-Present)
  • Ad hoc reviewer for 33 journals (2013-present)
  • Editorial board member of Journal of Dental Research (2016-2022)
  • 28 invited talks (nationally and internationally) (2013-2021)

Teaching Interests

  • Nano-Biomaterials and Regenerative Medicine (Course Director)
  • Responsible Conduct in Biomedical Research (Course Director)
  • Cell and Molecular Biology of Oral and Craniofacial Tissues II (Co-Course Director)
  • Microscopy, Imaging, and Associated Techniques (Co-course Director)

Recent Grants

  • NIH/NIDCR DE029808                                                          Liu (PI)           4/2021 - 3/2026
  • NIH/NIDCR DE024979                                                          Liu (PI)           7/2020-6/2022
  • NIH/NIAMS AR078311                                                          Liu (CO-I)       7/2021-3/2026
  • NIH/NIDCR AR078311                                                          Liu (Co-I)       7/2021-3/2026
  • NIH/NIDCR DE024979                                                          Liu (PI)          7/2016-6/2022
  • NIH/NIDCR DE019463                                                          Liu (Co-I)       7/2017-4/2022
  • CPRIT RP170179                                                                  Liu (Co-PI)    8/2017-8/2021 

Publications

2021 Dental pulp stem cell polarization: effects of biophysical factors
Chang B, Ma C, Feng J, Svoboda K, and Liu X (2021). “Dental pulp stem cell polarization: effects of biophysical factors” Journal of Dental Research, 100:1153-1160. PMID: 34328032
2021 Pyrophosphate inhibits periodontal ligament stem cell differentiation and mineralization through MAPK signaling pathways
Liang Y, Hu Z, Li Q, and Liu X (2021). “Pyrophosphate inhibits periodontal ligament stem cell differentiation and mineralization through MAPK signaling pathways” Journal of Periodontology Research, 56:982–990, PMID: 34142719
2021 Multifunctional polyplex micelles for efficient microRNA delivery and accelerated osteogenesis
Li Q, Hu Z, Rong X, Chang B, and Liu X (2021). “Multifunctional polyplex micelles for efficient microRNA delivery and accelerated osteogenesis” Nanoscale, 3: 12198–12211, PMID: 34231613
2021 Osteon: structure, turnover and regeneration
Chang B and Liu X (2021). “Osteon: structure, turnover and regeneration” Tissue Engineering Part B, 2021, doi: 10.1089/ten.TEB.2020.0322, PMID: 33487116
2021 Multifunctional peptide-conjugated non-viral gene delivery for vascularized pulp regeneration in a full-length human tooth root
Li Q, Hu Z, Liang Y, and Liu X (2021). “Multifunctional peptide-conjugated non-viral gene delivery for vascularized pulp regeneration in a full-length human tooth root” Acta Biomaterialia, 127: 252-265 PMID: 33813092.
2020 Nanofibrous tubular three-dimensional platform for single dental pulp stem cell polarization
Chang B, Ma C, and Liu X (2020). “Nanofibrous tubular three-dimensional platform for single dental pulp stem cell polarization” ACS Applied Materials & Interfaces, 12: 54481-54488, PMID: 33252216.
2020 ECM-mimicking nanofibrous matrix coaxes macrophages toward an anti-inflammatory phenotype: Cellular behaviors and transcriptome analysis
Wu R, Ma C, Liang Y, Chen F, and Liu X (2020). “ECM-mimicking nanofibrous matrix coaxes macrophages toward an anti-inflammatory phenotype: Cellular behaviors and transcriptome analysis” Applied Materials Today, 100508, PMCID: PMC7450828
2020 Recent advances in periodontal regeneration: A biomaterial perspective
Liang Y, Luan X, and Liu X (2020). “Recent advances in periodontal regeneration: A biomaterial perspective” Bioactive Materials, 5:297-308, PMCID: PMC7052441
2019 Osteoclasts in bone regeneration under type 2 diabetes mellitus
Hu Z, Ma C, Liang Y, Zou S, and Liu X (2019). “Osteoclasts in bone regeneration under type 2 diabetes mellitus” Acta Biomaterialia, 84:402-413. PMCID: PMC6326860
2019 Cell polarization: From epithelial cells to odontoblasts
Chang B, Svoboda K, and Liu X (2019). “Cell polarization: From epithelial cells to odontoblasts” International Journal of Oral Science, 98:1-11. PMCID: PMC6338482
2018 Bio-inspired micropatterned platforms recapitulate 3D physiological morphologies of bone and dentinal cells
Ma C, Chang B, Jing Y, Kim H, and Liu X (2018). “Bio-inspired micropatterned platforms recapitulate 3D physiological morphologies of bone and dentinal cells” Advanced Sciences, 5:1801037, PMCID:PMC6299721
2018 Nanofibers regulate single bone marrow stem cell osteogenesis via FAK/RhoA/YAP1 pathway
Chang B, Ma C, and Liu X (2018). “Nanofibers regulate single bone marrow stem cell osteogenesis via FAK/RhoA/YAP1 pathway” ACS Applied Materials & Interfaces, 10:33022-33031. PMCID: PMC6436105
2018 Immunomodulatory ECM-like microspheres for accelerated bone regeneration in diabetes mellitus
Hu Z, Ma C, Rong X, Zou S, and Liu X (2018). “Immunomodulatory ECM-like microspheres for accelerated bone regeneration in diabetes mellitus” ACS Applied Materials & Interfaces, 10:2377-2390. PMID: 29280610.
2018 3D maskless micropatterning for regeneration of highly organized tubular tissues
Ma C, Qu T, Chang B, Jing Y, Feng JQ, and Liu X. (2018) “3D maskless micropatterning for regeneration of highly organized tubular tissues” Advanced Healthcare Materials, 7: 1700738, PMCID: PMC5803393.
2017 Injectable scaffolds for dental and craniofacial regeneration
Chang B, Ahuja N, Ma C, and Liu X. (2017) “Injectable scaffolds for dental and craniofacial regeneration” Materials Science & Engineering R: Reports, 111:1-26. PMCID: PMC5478172.